James Franco played George in the adaptation of the John Steinbeck novel.
Dennis Quaid, left, is known as the star of films such as "Great Balls of Fire," "Wyatt Earp" and "The Parent Trap." His brother, character actor Randy Quaid, has appeared in "Brokeback Mountain" and "Kingpin."Jessica Simpson, left, and Ashlee Simpson Ross both had hot singing careers in the aughts.
It works both ways: Family members get drafted into the franchise, and former contestants make their own sibling introductions.The Kardashian family has made a name for themselves through their namesake reality show, "Keeping Up with the Kardashians." Pictured, from left, television personalities Rob Kardashian, Kim Kardashian, Kourtney Kardashian, Khloe Kardashian, Kylie Jenner, mom Kris Jenner and Kendall Jenner.From left, Keenen Ivory Wayans, Shawn Wayans, Marlon Wayans and Damon Wayans have built a comedic dynasty in Hollywood with shows like "In Living Color" and "The Wayans Bros." as well as the film spoofs "I'm Gonna Git You Sucka" and "Don't Be a Menace to South Central While Drinking Your Juice in the Hood."Mary-Kate, right, and Ashley Olsen, left, had early success sharing the role of Michelle Tanner on the sitcom "Full House." Elizabeth Olsen was a child actor, too, appearing in Mary-Kate and Ashley's movies.Sort of like that time you thought you’d found the perfect match for your brother while you were all at summer camp together? The current Bachelorette, Jo Jo Fletcher, isn’t the first in her family to look for love on a reality show — though outside of the Bachelor franchise.Her brother Ben Patton was on Eva Longoria’s short-lived dating show, “Ready for Love,” in 2013 and perhaps that’s part of the reason he (accurately) questioned Higgins’s affection for his sister.Once you’re in the game, you’re playing for that one big love.Should you fail the first time around (and most everyone does!They stayed together for two-and-a-half years before divorcing, and Jennifer went on to date her Alias co-star Michael Vartan. Rachel went on to date Hayden Christensen, while Adam has reportedly found love with another TV darling, Leighton Meester.Before tying the knot with Ryan Reynolds in 2012, Blake Lively was coupled up with her Gossip Girl co-star Penn Badgley.Nina Dobrev and Ian Somerhalder reportedly split in May 2013 after more than three years of dating.The couple met while playing star-crossed lovers Elena and Damon on The Vampire Diaries and will likely be seeing lots of each other when the show resumes filming later this year.